Aging can be defined as functional decline in the physiological integrity of a living organism
over time. It can lead to disruption in homeostasis not only at whole organism level but also
at tissue, cellular, and genomic level. Cellular and molecular hallmarks of aging include
stem cell exhaustion, cellular senescence, telomere attrition, loss of proteostasis,
deregulated nutrient sensing, mitochondrial dysfunction, genomic instability, epigenetic
alterations, and inflammation. 1 Aging is a risk factor for many neurodegenerative disorders …