KEGG Mapper for inferring cellular functions from protein sequences

M Kanehisa, Y Sato - Protein Science, 2020 - Wiley Online Library
M Kanehisa, Y Sato
Protein Science, 2020Wiley Online Library
KEGG is a reference knowledge base for biological interpretation of large‐scale molecular
datasets, such as genome and metagenome sequences. It accumulates experimental
knowledge about high‐level functions of the cell and the organism represented in terms of
KEGG molecular networks, including KEGG pathway maps, BRITE hierarchies, and KEGG
modules. By the process called KEGG mapping, a set of protein coding genes in the
genome, for example, can be converted to KEGG molecular networks enabling interpretation …
Abstract
KEGG is a reference knowledge base for biological interpretation of large‐scale molecular datasets, such as genome and metagenome sequences. It accumulates experimental knowledge about high‐level functions of the cell and the organism represented in terms of KEGG molecular networks, including KEGG pathway maps, BRITE hierarchies, and KEGG modules. By the process called KEGG mapping, a set of protein coding genes in the genome, for example, can be converted to KEGG molecular networks enabling interpretation of cellular functions and other high‐level features. Here we report a new version of KEGG Mapper, a suite of KEGG mapping tools available at the KEGG website (https://www.kegg.jp/ or https://www.genome.jp/kegg/), together with the KOALA family tools for automatic assignment of KO (KEGG Orthology) identifiers used in the mapping.
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